SELECTED PUBLICATIONS

2019

  • Faitg J, Leduc-Gaudet JP, Reynaud O, Ferland G, Gaudreau P, Gouspillou G, Effects of Aging and Caloric Restriction on Fiber Type Composition, Mitochondrial Morphology and Dynamics in Rat Oxidative and Glycolytic Muscles. Frontiers in Physiology - Striated Muscle Physiology, 2019, 10:420. | Pubmed

  • Leduc-Gaudet JP, Reynaud O, Hussain SN, Gouspillou G., Parkin overexpression protects from aging-related loss of muscle mass and strength, The Journal of Physiology, 2019, 597(7):1975-1991. | Pubmed

  • 2018

  • Gouspillou G, Godin R, Piquereau J, Picard M, Mofarrahi M, Mathew J, Purves-Smith FM, Sgarioto N, Hepple RT, Burelle Y, Protective role of Parkin in skeletal muscle contractile and mitochondrial function, The Journal of Physiology, 2018, 596(13):2565-2579. | Pubmed

  • Leduc-Gaudet JP, Reynaud O, Chabot F, Mercier J, Andrich DE, St-Pierre DH, Gouspillou G, The impact of a short-term high-fat diet on mitochondrial respiration, reactive oxygen species production, and dynamics in oxidative and glycolytic skeletal muscles of young rats. Physiol Rep. 2018 Feb;6(4). doi: 10.14814/phy2.13548. | Pubmed

  • 2017

  • St-Jean-Pelletier F, Pion CH, Leduc-Gaudet JP, Sgarioto N, Zovilé Í, Barbat-Artigas S, Reynaud O, Alkaterji F, Lemieux FC, Grenon A, Gaudreau P, Hepple RT, Chevalier S, Belanger M, Morais JA, Aubertin-Leheudre M & Gouspillou G,The impact of ageing, physical activity, and pre-frailty on skeletal muscle phenotype, mitochondrial content, and intramyocellular lipids in men. The Journal of Cachexia, Sarcopenia and Muscle, 2017 Apr;8(2):213-228. | Pubmed

  • 2016

  • Gouspillou G and Hepple RT, Mitochondria in skeletal muscle health, aging and diseases, Frontiers in Physiology, Striated muscle Physiology 2016 Oct 6;7:446. eCollection 2016. | Pubmed

  • Spendiff S, Vuda M, Gouspillou G, Aare S, Perez A, Morais JA, Jagoe RT, Filion ME, Glicksman R, Kapchinsky S, MacMillan N, Pion CH, Aubertin-Leheudre M, Hettwer S, Correa JA, Taivassalo T, Hepple RT, Denervation drives mitochondrial dysfunction in skeletal muscle of octogenarians. J. Physiol. 2016, Sep 13. doi: 10.1113/JP272487 | Pubmed

  • 2015

  • Diolez P., Bourdel-Marchasson I., Calmettes G., Padois P., Detaille D., Rouland R. and Gouspillou G, Hypothesis on skeletal muscle aging : mitochondrial adenine nucleotide translocator decreases reactive oxygen species production while preserving coupling efficiency, Frontiers in Physiology, Striated muscle Physiology 2015, 16;6:369. doi: 10.3389/fphys.2015.00369.
    | Pubmed

  • Leduc-Gaudet J.P., Auger M.J., St-Jean Pelletier F. and Gouspillou G, Towards a better understanding of the role played by mitochondrial dynamics and morphology in skeletal muscle atrophy, J. Physiol. 2015, 593(14): 2993-2994. PubMed Link
    | Pubmed

  • Leduc-Gaudet J.P., Picard M, St-Jean Pelletier F., Sgarioto N, Auger M.J., Vallée J., Robitaille R., St-Pierre D.H. and Gouspillou G, Mitochondrial morphology is altered in atrophied skeletal muscle of aged mice, Oncotarget 2015, Advanced Publicaiton (ahead of print).
    | Pubmed

  • Gouspillou G, Scheede-Bergdahl C, Spendiff S, Vuda M, Meehan B, Mlynarski H, Archer-Lahlou E, Sgarioto N, Purves-Smith FM, Konokhova Y, Rak J, Chevalier S, Taivassalo T, Hepple RT, Jagoe RT., Anthracycline-containing chemotherapy causes long-term impairment of mitochondrial respiration and increased reactive oxygen species release in skeletal muscle., Sci Rep. 2015, 5:8717.
    | Pubmed

  • 2014

  • Gouspillou G, Sgarioto N, Norris B, Barbat-Artigas S, Aubertin-Leheudre M, Morais JA, Burelle Y, Taivassalo T, Hepple RT., The relationship between muscle fiber type-specific PGC-1α content and mitochondrial content varies between rodent models and humans, PLoS One, 2014 Aug 14;9(8): e103044.
    | Pubmed

  • Gouspillou G, Sgarioto N, Kapchinsky S, Purves-Smith F, Norris B, Pion CH, Barbat-Artigas S, Lemieux F, Taivassalo T, Morais JA, Aubertin-Leheudre M, Hepple RT, Increased sensitivity to mitochondrial permeability transition and myonuclear translocation of endonuclease G in atrophied muscle of physically active older humans, FASEB J. 2014 Apr;28(4):1621-33.
    | Pubmed

  • Gouspillou G, Bourdel-Marchasson I, Rouland R, Calmettes G, Biran M, Deschodt-Arsac V, Miraux S, Thiaudiere E, Pasdois P, Detaille D, Franconi JM, Babot M, Trézéguet V, Arsac L, Diolez P, Mitochondrial energetics is impaired in vivo in aged skeletal muscle, Aging Cell. 2014 Feb;13(1):39-48.
    | Pubmed

  • 2013

  • Gouspillou G, Picard M, Godin R, Burelle Y, Hepple RT, Role of peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) in denervation-induced atrophy in aged muscle: facts and hypotheses, Longev Healthspan. 2013 Aug 1;2(1):13.
    | Pubmed

  • Mofarrahi M, Guo Y, Haspel JA, Choi AM, Davis EC, Gouspillou G, Hepple RT, Godin R, Burelle Y, Hussain SN, Autophagic flux and oxidative capacity of skeletal muscles during acute starvation, Autophagy. 2013 Oct 1;9(10):1604-20.
    | Pubmed

  • Gouspillou G, Hepple RT, Facts and controversies in our understanding of how caloric restriction impacts the mitochondrion,Exp Gerontol. 2013 Oct;48(10):1075-84.
    | Pubmed

  • 2011

  • Picard M, Taivassalo T, Gouspillou G, Hepple RT, Mitochondria: isolation, structure and function,J Physiol. 2011 Sep 15;589(Pt 18):4413-21 | Pubmed

  • Gouspillou G, Rouland R, Calmettes G, Deschodt-Arsac V, Franconi JM, Bourdel-Marchasson I, Diolez P, Accurate determination of the oxidative phosphorylation affinity for ADP in isolated mitochondria, PLoS One. 2011;6(6):e20709.
    | Pubmed

  • 2010

  • Gouspillou G, Bourdel-Marchasson I, Rouland R, Calmettes G, Franconi JM, Deschodt-Arsac V, Diolez P, Alteration of mitochondrial oxidative phosphorylation in aged skeletal muscle involves modification of adenine nucleotide translocator, Biochim Biophys Acta. 2010 Feb;1797(2):143-51.
    | Pubmed

  • Full list of publications : Pubmed

  • Faculté des Sciences, UQÀM